Regadenoson是一種A2A腺苷受體激動劑是一種冠狀動脈血管擴張劑。
適應證:Lexiscan是一種藥理學應激劑適用于在不能進行適當運動負荷患者中放射性核素心肌灌注顯像(MPI)。
劑量和用法:Lexiscan推薦的劑量是5 mL (0.4 mg regadenoson)通過迅速靜脈注射;隨后立即用鹽水和放射性藥物沖洗。
禁忌證:有二級或三級AV阻滯,或竇房結功能失調患者不能給予Lexiscan除非患者 有功能良好的人工心臟起搏器
不良反應:對Lexiscan最常見(發生率 ≥ 5%)不良反應是呼吸困難、頭痛、面紅、胸部不適、眩暈、心絞痛、胸痛、和惡心。
藥物相互作用:甲基黃嘌吟類,如,咖啡因和茶堿,可能干擾Lexiscan的活性。 氨茶堿可能用于減輕嚴重和/或對Lexiscan的持久不良反應。
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